摘要

       污水处理厂的抗生素抗性基因（ARGs）和毒力基因（VGs）如果不进行适当的处理，可能对公众健康造成潜在威胁。利用地球化学方法揭示了膜生物反应器（MBR）和氧化沟（OD）中ARG/VG多样性的差异以及ARGs和VGs的时间共生模式。结果表明，由于MBR具有较好的消毒能力，短期内其ARGs和VGs的多样性低于OD。但是，由于温度的巨大变化，两个反应器之间的差异在长期内消失了。相反，观察到时间衰减关系，总周转率为-0.0105。共生模式表明，由于ARGs和VGs对环境变化的响应不同，ARGs和VGs之间的直接联系随着时间的增加而急剧减少。

       Antibiotic resistance genes (ARGs) and virulence genes (VGs) in wastewater treatment plants (WWTPs) may pose a potential threat to public health if without proper treatment. In this study, GeoChip was used to reveal the differences in ARG/VG diversity between a membrane bioreactor (MBR) and an oxidation ditch (OD) and the temporal co-occurrence patterns between ARGs and VGs. Results showed that the diversity of ARGs and VGs was lower in MBR than that in OD in the short term due to the better disinfection capability of MBR. However, the differences in diversity between two reactors disappeared in the long term because of the great variation of temperature. Instead, time-decay relationship was observed and overall turnover rate was -0.0105. Co-occurrence patterns indicate that direct connections between ARGs and VGs reduced sharply with time increasing due to the different responses of ARGs and VGs to environmental variation.

       https://www.sciencedirect.com/science/article/pii/S0160412019317477?via%3Dihub