摘要

      抗生素在水产养殖中的广泛应用可能导致抗药性基因（ARGs）的出现，并通过进入食物链威胁人类健康。为评价抗生素对我国环境的危害，根据8个池塘的水源、池塘水和沉积物中11种ARG的含量，测定了8种抗生素的时空分布和相关性。结果表明，苏尔1是水体和池塘水中的主要ARGs，tetC是沉积物中的主要ARGs。随着养殖密度和塘龄的增加，ARGs含量呈增加趋势。与单一养殖相比，虾养殖结合不同营养水平的养鱼可以影响ARGs的丰度。沉积物中ARGs的含量与抗生素的浓度也有显著的相关性，而在水源和池塘水中则没有相关性。

      The widespread use of antibiotics in aquaculture can potentially lead to the emergence of antibiotic resistance genes (ARGs) and threaten human health by entering the food chain. To assess the environmental risk posed by antibiotics in China, the spatial-temporal distribution and correlation of 8 antibiotics based on the abundance of 11 ARGs in water sources, pond water, and sediment in 8 ponds were determined. The results indicated that sul1 was the predominant ARG in water sources and pond water, and tetC was the most in the sediment. A trend of increasing abundance of ARGs was observed with increased rearing density and pond age. Compared to monoculture, shrimp culture integrated with different trophic levels of fish farming could influence the abundance of ARGs. There was also a significant correlation between the abundance of ARGs and antibiotic concentration in the sediment, while no correlation was observed in water sources and pond water.

       https://www.sciencedirect.com/science/article/abs/pii/S0025326X18308142?via%3Dihub