摘要
抗生素抗性基因(ARGs)是普遍存在的,但只有当存在于病原体时才会引起问题。 抗生素抗性的选择和传递频繁发生的环境可能具有ARGs水平转移的高浓度和多样性的特征。然而,包括人类和动物在内的大多数环境类型在内,缺乏大规模ARG的定量数据和潜在的共同选择性试剂(如杀生物剂和金属)的抗性基因的数据。 这些数据的缺乏妨碍了环境风险的有效识别。
Antibiotic resistance genes (ARGs) are widespread but cause problems only when present in pathogens. Environments where selection and transmission of antibiotic resistance frequently take place are likely to be characterized by high abundance and diversity of horizontally transferable ARGs. Large-scale quantitative data on ARGs is, however, lacking for most types of environments, including humans and animals, as is data on resistance genes to potential co-selective agents, such as biocides and metals. This paucity prevents efficient identification of risk environments.
来源https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-016-0199-5