摘要

    水环境中的抗生素抗性基因（ARG）已成为全球健康问题。 猪废水被广泛认为是在水环境中促进ARGs增殖的主要因素之一。 本文全面回顾和讨论了厌氧处理猪废水中ARGs的发生和去除，以及抗生素对ARGs命运的贡献。 结果表明，厌氧过程中ARGs的去除不稳定，这与抗生素的存在负相关。 携带ARGs的细菌的丰富度随着抗生素的添加而增加，并导致ARGs的扩散。 在本综述中，发现抗生素与ARG的丰富和转移之间存在正相关。 但是，有必要了解抗生素，ARGs和微生物群落之间的相关性，并获得更多有关控制ARGs在环境中传播的知识。

    Antibiotic resistance genes (ARGs) in water environment have become a global health concern. Swine wastewater is widely considered to be one of the major contributors for promoting the proliferation of ARGs in water environments. This paper comprehensively reviews and discusses the occurrence and removal of ARGs in anaerobic treatment of swine wastewater, and contributions of antibiotics to the fate of ARGs. The results reveal that ARGs’ removal is unstable during anaerobic processes, which negatively associated with the presence of antibiotics. The abundance of bacteria carrying ARGs increases with the addition of antibiotics and results in the spread of ARGs. The positive relationship was found between antibiotics and the abundance and transfer of ARGs in this review. However, it is necessary to understand the correlation among antibiotics, ARGs and microbial communities, and obtain more knowledge about controlling the dissemination of ARGs in the environment.

    https://www.sciencedirect.com/science/article/abs/pii/S0960852419318838