摘要

    环境中的抗生素抗性细菌（ARB）和抗生素抗性基因（ARG）由于对人体健康的潜在风险而备受关注。废水处理厂和畜牧生产产生的废水是ARB和ARG的主要来源。氯化，紫外线照射和臭氧消毒无法完全去除ARG。在这项研究中，作为细胞内和细胞外形式的ARB和ARGs失活的替代处理技术，电化学氧化和Fenton工艺的潜力得到了评估。结果表明，电化学氧化过程对于所选ARB的灭活是有效的，但对于细胞内ARG或细胞外ARG的去除却无效。 Fenton电过程对于去除细胞内和细胞外ARG均更有效。在存在1.0 mmol / C的条件下，在21.42 mA / cm2的条件下进行120分钟的电芬顿处理后，去除效率分别为：细胞内tetA 3.8 log，细胞内ampC 4.1 log，细胞外tetA 5.2 log和细胞外ampC 4.8 log。 L Fe2 +。有人提出，电化学氧化是一种有效的ARB消毒方法，而电子芬顿工艺是一种去除废水中细胞内和细胞外ARG的有前途的技术。

    Antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) in the environment are of great concern due to their potential risk to human health. The effluents from wastewater treatment plants and livestock production are major sources of ARB and ARGs. Chlorination, UV irradiation, and ozone disinfection cannot remove ARGs completely. In this study, the potential of electrochemical oxidation and electro-Fenton processes as alternative treatment technologies for inactivation of ARB and ARGs in both intracellular and extracellular forms was evaluated. Results showed that the electrochemical oxidation process was effective for the inactivation of selected ARB but not for the removal of intracellular ARGs or extracellular ARGs. The electro-Fenton process was more effective for the removal of both intracellular and extracellular ARGs. The removal efficiency after 120 min of electro-Fenton treatment under 21.42 mA/cm2 was 3.8 logs for intracellular tetA, 4.1 logs for intracellular ampC, 5.2 logs for extracellular tetA, and 4.8 logs for extracellular ampC, respectively in the presence of 1.0 mmol/L Fe2+. It is suggested that electrochemical oxidation is an effective disinfection method for ARB and the electro-Fenton process is a promising technology for the removal of both intracellular and extracellular ARGs in wastewater.

    https://iwaponline.com/wst/article/81/10/2221/74726/Inactivation-of-antibiotic-resistant-bacteria-and