摘要

对在食品生产中使用抗生素的日益关注导致了许多关于动物相关细菌群落中抗生素抗性基因 (ARG) 发生的研究。 在很少或不使用抗生素的情况下集约饲养鸡的农场中，关于 ARG 丰度的基线数据很少。 本研究使用高通量定量 PCR 阵列来调查两个无抗生素养鸡场的 ARG 和已知可增强 ARG 传播的移动遗传元件的发生。 在本研究之前的五年内，研究农场没有使用抗生素。 结果为没有直接选择压力的鸡生产系统中抗性基因的出现提供了基线。

  Rising concern about the use of antibiotics in food production has resulted in many studies on the occurrence of antibiotic resistance genes (ARGs) in animal-associated bacterial communities. There are few baseline data on the abundance of ARGs on farms where chickens are intensively raised with little or no use of antibiotics. This study used a high-throughput quantitative PCR array to survey two antibiotic-free chicken farms for the occurrence of ARGs and mobile genetic elements known to enhance the spread of ARGs. No antibiotics had been used on the study farms for five years prior to this study. The results provide a baseline for the occurrence of resistance genes in the chicken production system without direct selective pressure. View Full-Text
  https://www.mdpi.com/2079-6382/9/3/120