摘要

  诺氟沙星 (NFLX) 是一种合成抗生素，广泛用于治疗传染病。在这项工作中，研究了微生物燃料电池 (MFC) 在 NFLX 降解、发电和抗生素抗性基因 (ARG) 生成方面的性能。 NFLX降解效率和COD去除率分别达到65.5%和94.5%。 NFLX 浓度的增加 (128 mg/L) 对 NFLX 降解效率、COD 去除率和 MFCs 电压输出没有显着影响，同时成功发电。定量聚合酶链反应 (qPCR) 表明与传统废水处理厂 (WWTP) 相比，ARG（mdtk、mdtm 和 pmra）的绝对丰度较低。阳极细菌可以在高 NFLX 浓度的情况下存活并维持其降解和发电。在 NFLX 降解、COD 去除、减少 ARGs 生成和同时产生能量方面，MFC 似乎是一种很有前途的抗生素废水处理技术，有可能克服 ARGs 挑战。

  Norfloxacin (NFLX) is a synthetic antibiotic widely used in the treatment of infectious diseases. In this work, the performance of microbial fuel cells (MFCs) toward NFLX degradation, electricity production and the antibiotics resistances genes (ARGs) generation was investigated. NFLX degradation efficiency and COD removal reached 65.5% and 94.5% respectively. The increase in NFLX concentration (128 mg/L) had no significant influence on NFLX degradation efficiency, COD removal and MFCs voltage output while the electricity was successfully generated. The quantitative polymerase chain reaction (qPCR) indicated low absolute abundances of ARGs (mdtk, mdtm, and pmra) compared with the traditional wastewater treatment plants (WWTPs). Anodic bacteria can survive in the presence of high NFLX concentration and sustain its degradation and electricity production. In terms of NFLX degradation, COD removal, diminished ARGs generation and simultaneous energy production, MFC seems to be a promising technology for antibiotics wastewater treatment with a potential to overcome the ARGs challenge.

  https://www.sciencedirect.com/science/article/abs/pii/S0960852420302534