摘要

       抗生素是日益增多的环境污染物，导致公众健康问题。 抗生素通常用作家禽饲料中的生长促进剂和治疗剂，它们在鸡的身体组织中没有完全代谢，作为母体化合物沉积在肉中，最终通过家禽粪便排泄到环境中。 土壤中的这些抗生素通过激活抗生素抗性基因 (ARG) 导致细菌产生抗生素抗性。 ARGs 和抗生素抗性细菌 (ARB) 的发展导致巨大的物理和经济损失，因为这些细菌无法用常用抗生素治疗。 而且，这些抗生素进入食物链后，严重影响人体免疫系统、生长发育和机体代谢。 因此，为了降低抗生素未来的健康风险，迫切需要了解家禽抗生素的命运和 ARGs 在土壤环境中的传播。

       Antibiotics are growing environmental contaminants leading to public health concern. Antibiotics are commonly used as growth promoters and therapeutic agents in poultry feed that are not completely metabolized in the body tissues of chicken, get deposited in meat as parent compounds, and ultimately excreted via poultry droppings into the environment. These antibiotics in the soil result into the creation of antibiotic resistance in bacteria via activation of antibiotic resistance genes (ARGs). The development of ARGs and antibiotic-resistant bacteria (ARB) lead to huge physical and economic losses, as these bacteria cannot be treated with commonly used antibiotics. Moreover, these antibiotics after entering into food chains seriously affect the human immune system, growth, and metabolism of the body. Therefore, to reduce the future health risks of antibiotics, there is a dire need to understand the fate of poultry antibiotics and spread of ARGs in the soil environment.
https://link.springer.com/article/10.1007/s11368-019-02360-0