摘要

       处理混合城市污水和工业废水的城市污水处理厂 (UWTP) 是抗生素抗性基因 (ARG) 传播到环境中的主要热点之一。本研究通过在有和没有工业废水的情况下运行工厂，解决了废水来源对全面 UWTP（15,000 人口当量，PE）中 ARG 动态的影响。来自不同处理点的复合样品 (4L) 的化学成分、细菌丰度和四种抗四环素、磺胺类、红霉素和喹诺酮类耐药基因的丰度（tetA、sul2、ermB 和 qnrS），以及1 类积分子 (intI1)。尽管当工厂在有或没有工业废水的情况下运行时，流出物的化学成分显着不同，但系统在去除细菌细胞、ARG 和 intI1 方面的效率是恒定的。过氧乙酸 (PAA) 的最终消毒不影响 ARG 的去除，这与废水来源和流入的化学特性无关。我们的结果表明，一个运行良好的小型 UWTP 可以处理混合在城市污水中的大量工业废水，而不会影响整体 ARGs 和释放到环境中的 1 类整合子。

       Urban Wastewater Treatment Plants (UWTPs) treating mixed urban sewage and industrial wastewater are among the major hotspots for the spread of Antibiotic Resistance Genes (ARGs) into the environment. This study addresses the impact of the wastewater origin on ARG dynamics in a full-scale UWTP (15,000 Population Equivalent, PE) by operating the plant with and without industrial wastewater. Composite samples (4 L) from different treatment points were characterized for their chemical composition, bacterial abundance and for the abundance of four resistance genes against tetracycline, sulfonamides, erythromycin, and quinolones (tetA, sul2, ermB, and qnrS), and of the class 1 integrons (intI1). Although the chemical composition of the outflow significantly differed when the plant operated with or without industrial wastewater, the system efficiency in the removal of bacterial cells, ARGs, and intI1 was constant. The final disinfection by peracetic acid (PAA) did not affect the removal of ARGs, independently of the wastewater origin and the chemical characteristics of the inflows. Our results demonstrated that a well-functioning small size UWTP could treat a significant amount of industrial wastewater mixed in the urban sewage without affecting the overall ARGs and class 1 integrons released into the environment.

https://www.sciencedirect.com/science/article/abs/pii/S0048969718328663