摘要
      反渗透（RO）工艺已广泛应用于工业和饮用水回用的废水回收。为了防止生物淤积，通常在预处理中使用氯消毒。然而，这项研究发现，氯消毒会显著增加反渗透系统中抗生素抗性基因（ARGs）的风险。随着氯浓度从0增加到5mg/L，膜污染物中14种常见ARGs的累积相对丰度增加了49.6%。在这些ARGs中，tolC、acrA和acrB（对多种药物的耐药性）在氯消毒后表现出最高的增加。特别是，与对照组相比，5 mg/L氯组的tolC相对丰度增加了113.3%。这些ARGs往往在一些细菌属中富集，包括Candidatus、Thiomonas、Silanimonas、Xanthomonas和Pseudomonas。这些结果表明，反渗透膜上的污染物可能成为ARGs的潜在汇点。考虑到膜破裂的可能性，ARGs可能会污染渗透物并带来巨大的生物风险。
Abstract
The reverse osmosis (RO) process has been applied extensively in wastewater reclamation for industrial and potable reuse. To prevent biofouling, chlorine disinfection was usually used in pretreatment. However, this study found that chlorine disinfection could significantly increase risks of antibiotic resistant genes (ARGs) in the RO system. With the increase of chlorine concentration from 0 to 5 mg/L, the accumulative relative abundance of 14 common ARGs in the membrane foulants increased by 49.6%. Among these ARGs, tolC, acrA and acrB (resistance to multiple drugs) showed the highest increament after chlorine disinfection. Especially, the relative abundance of tolC in the group with 5 mg/L chlorine increased by 113.3% compared with the control group. These ARGs tended to be enriched in a few bacterial genus, including Candidatus, Thiomonas, Silanimonas, Xanthomonas and Pseudomonas. These results indicated that the foulants on RO membranes might become a potential sink of ARGs. Considering the possibility of membrane breach, the ARGs may contaminate the permeate and bring great biological risks.

https://www.sciencedirect.com/science/article/abs/pii/S0048969721079390