摘要
       抗生素耐药性的流行，以及作为抗生素耐药性细菌（ARB）和抗生素耐药性基因（ARGs）载体的微塑料（MP）越来越受到关注。然而，人们对氯化和芬顿氧化处理的MPs上ARB/ARGs的命运知之甚少。本文比较分析了氯化和芬顿氧化后，垃圾渗滤液（垃圾渗滤液和ARG的重要储库）周围的垃圾渗滤液上和垃圾渗滤液中ARG/ARB的去除和再生。MPs上的目标ARGs的减少明显小于渗滤液中的目标ARG，氯化后的最大百分比减少为34.0–46.3%，而54.3–77.6%，芬顿氧化后的最大比例减少为92.1–97.3%，而>99.9%，并且观察到ARB的类似去除模式。此外，在氯化（5、10、20和50mg/L）结束时储存48小时后，发现渗滤液中的ARGs/ARB有相当大的再生，并且在MPs上ARGs和ARB的再生量更大，分别高达17倍和139倍。相比之下，芬顿氧化实现了目标ARG/ARB的再生生长减少。这些发现表明，MPs上的ARGs/ARB比渗滤液中的ARGs/ARB更难去除，渗滤液中，尤其是MPs上的ARGs/ARB在氯化后表现出相当大的快速再生潜力。
Abstract
The prevalence of antibiotic resistance, as well as microplastics (MPs) as vectors for antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) has attracting growing attention. However, the fate of ARB/ARGs on MPs treated by chlorination and Fenton oxidation were poorly understood. Herein, the removal and regrowth of ARGs/ARB on MPs and in MPs-surrounding landfill leachate (an important reservoir of MPs and ARGs) after chlorination and Fenton oxidation were comparatively analyzed. Target ARGs on MPs were reduced obviously less than that in leachate, with the largest percentages reduction of 34.0–46.3% vs. 54.3–77.6% after chlorination and 92.1–97.3% vs. > 99.9% after Fenton oxidation, and similar removal patterns were observed for ARB. Moreover, a considerable regrowth of ARGs/ARB in leachate were found after 48 h of storage at the end of chlorination (5, 10, 20 and 50 mg/L), and a greater regrowth of ARGs and ARB occurred on MPs with up to 17 and 139 fold, respectively. In contrast, Fenton oxidation achieved a reduced regrowth of target ARGs/ARB. These findings indicated that the removal of ARGs/ARB on MPs were more difficult than that in leachate, and ARGs/ARB in leachate and especially on MPs exhibited a considerable potential for rapid regrowth after chlorination.

https://www.sciencedirect.com/science/article/abs/pii/S0304389422002205