摘要
      垃圾填埋场是抗生素和抗生素抗性基因（ARGs）的重要宿主。它们含有多种污染物，如重金属和持久性有机化学物质、复杂的微生物群落和厌氧降解过程，这有助于ARGs和抗生素抗性细菌（ARB）的发生、发展和转移。主要担心的是抗生素和已开发的ARGs和ARB可能通过渗滤液和垃圾填埋场泄漏转移到当地环境中。在本文中，我们概述了已建立的关于垃圾填埋场中抗生素和ARGs的研究，总结了抗生素和ARG的起源和分布，讨论了各种抗生素、ARG和细菌群落之间的联系以及ARG的影响因素，并评估了目前抗生素和ARGs的处理过程。最后，提出了未来的研究来填补目前的知识空白，其中包括抗生素耐药性的发展和传播机制，以及抗生素耐药性的有效治疗方法。
Abstract
Landfill are important reservoirs of antibiotics and antibiotic resistance genes (ARGs). They harbor diverse contaminants, such as heavy metals and persistent organic chemicals, complex microbial consortia, and anaerobic degradation processes, which facilitate the occurrence, development, and transfer of ARGs and antibiotic resistant bacteria (ARB). The main concern is that antibiotics and developed ARGs and ARB may transfer to the local environment via leachate and landfill leakage. In this paper, we provide an overview of established studies on antibiotics and ARGs in landfills, summarize the origins and distribution of antibiotics and ARGs, discuss the linkages among various antibiotics, ARGs, and bacterial communities as well as the influencing factors of ARGs, and evaluate the current treatment processes of antibiotics and ARGs. Finally, future research is proposed to fill the current knowledge gaps, which include mechanisms for the development and transmission of antibiotic resistance, as well as efficient treatment approaches for antibiotic resistance.

https://www.sciencedirect.com/science/article/abs/pii/S0048969721057259