摘要
      缺乏对畜牧废水中生长的水草中抗生素和抗生素抗性基因（ARGs）的健康风险的研究。我们的研究结果表明，畜禽废水中的抗生素被水草吸收并生物累积。抗生素在根中的浓度高于在茎和叶中的浓度。水草中抗生素的健康风险系数低于阈值（<0.1），表明在本案例研究中，考虑到抗生素的积累，用于净化牲畜废水的水草对人类是安全的。ARGs在牲畜废水和水草中密切相关，结果显示，在牲畜废水中检测到的所有13种ARGs也都在水草中发现。在牲畜废水和水草中，四环素抗性基因比其他ARG更丰富。据估计，人类每天在水草中摄入的ARGs在2.06×106至7.75×1012拷贝g−1之间，这表明摄入水草中ARGs的潜在风险不容忽视。尽管本研究评估了食用用于净化牲畜废水的水草的安全性，考虑到累积的抗生素和ARGs，但仍应进行更多的研究，以确保我们充分了解其健康风险。
Abstract
Research is lacking on the health risks of antibiotics and antibiotic resistance genes (ARGs) in water dropwort grown in livestock wastewater. Our results showed that antibiotics from livestock wastewater were absorbed and bioaccumulated by water dropwort. The concentration of antibiotics was higher in the roots than in the stems and leaves. The health-risk coefficients of antibiotics in water dropwort were below the threshold (<0.1), indicating that in this case study, the consumption of water dropwort used to purify livestock wastewater was safe for humans considering accumulated antibiotics. ARGs were closely correlated between livestock wastewater and water dropwort, with the results showing that all 13 ARGs detected in the livestock wastewater were also found in the water dropwort. Tetracycline resistance genes were more abundant than the other ARGs in both the livestock wastewater and water dropwort. The estimated daily intake of ARGs in water dropwort for humans ranged from 2.06 × 106 to 7.75 × 1012 copies g−1, suggesting the potential risk of intaking ARGs in water dropwort cannot be ignored. Although the safety of consuming water dropwort used to purify livestock wastewater, considering accumulated antibiotics and ARGs, was assessed in this study, more studies should be conducted to ensure we fully understand the health risks.

https://www.mdpi.com/2079-6382/11/4/428