摘要

噬菌体和古细菌病毒通过溶原性转化或转导促成微生物基因组之间遗传物质的水平转移。 最近的基因组学，宏基因组学和单细胞研究表明，溶原性转化是普遍的，并为宿主提供适应性特征，通常与生物相互作用有关。 对转导的进化影响的量化已经落后，需要进一步的理论和实验工作。 然而，最近的研究表明，广义转导在抗生素抗性基因的转移和特定细菌内竞争的新基因获取中发挥作用。 转导和溶原性转化的特性补充其他转移机制的特性，并且可以在群落间适应性基因的扩散中起关键作用。

Bacteriophages and archaeal viruses contribute, through lysogenic conversion or transduction, to the horizontal transfer of genetic material between microbial genomes. Recent genomics, metagenomics, and single cell studies have shown that lysogenic conversion is widespread and provides hosts with adaptive traits often associated with biotic interactions. The quantification of the evolutionary impact of transduction has lagged behind and requires further theoretical and experimental work. Nevertheless, recent studies suggested that generalized transduction plays a role in the transfer of antibiotic resistance genes and in the acquisition of novel genes during intra-specific bacterial competition. The characteristics of transduction and lysogenic conversion complement those of other mechanisms of transfer, and could play a key role in the spread of adaptive genes between communities.

https://www.sciencedirect.com/science/article/pii/S1369527416301692