摘要

从根管治疗的牙齿顶端牙周炎中经常分离粪肠球菌，提出了该生物体在牙髓治疗失败中的作用。 已经在该生物体的致病性中提出了不同的因素。 在这项研究中，鉴定了22根来自牙根管的粪肠球菌分离物，并研究了表型和基因型特征。 没有注意到对万古霉素和庆大霉素的抗性，并且大多数分离株（91％）对氨苄青霉素敏感。 在73％的分离株中检测到生物膜形成，并且可以将其视为与这些分离株的发病机理有关的最重要的毒力因子。

Frequent isolation of Enterococcus faecalis from root canal treated teeth with apical periodontitis, has proposed the role of this organism in endodontic treatment failures. Different factors have been suggested in the pathogenicity of this organism. In this study, 22 E. faecalis isolates from canals of root-filled teeth were identified, and phenotypic and genotypic characteristics were investigated. No resistance to vancomycin and gentamicin was noted, and most isolates (91%) were susceptible to ampicillin. Biofilm formation was detected in 73% of the isolates and may be considered as the most important virulence factor involved in the pathogenesis of these isolates.

https://www.ncbi.nlm.nih.gov/pubmed/30600657