摘要

    在4个废水处理厂（WWTP），2个污水接收区（ERAs）和杭州湾（HZB）中分析了14种ARGs，intI1和16S rDNA的分布。 结果表明，每个集成的污水处理厂（IWWTP）收到的ARG的数量要高于药品污水处理厂（PWWTP），并且IWWTP去除ARG的效率要高于药品污水处理厂。 污水处理厂的废水在ERAs和HZB的水环境中对ARGs的污染做出了很大贡献，并且ARGs的总丰度呈现出距离衰减的规律。 在沿海沉积物中，更多的ARGs聚集在偏远地区。 相关分析表明，污水处理厂中ARGs的发生与16S rDNA和intI1更相关。 在所有样品组中，三个大环内酯类抗性基因（ermB，mphA和vatB）与16S rDNA和intI1密切相关。 我们的研究清楚地揭示了土地污水处理厂排放与沿海环境中ARGs的新兴污染之间的联系

    The distribution of 14 ARGs, intI1, and 16S rDNA were analysed in 4 wastewater treatment plants (WWTPs), 2 effluent receiving areas (ERAs), and Hangzhou Bay (HZB). The results showed that each integrated WWTP (IWWTP) received higher abundance of ARGs than pharmaceutical WWTPs (PWWTPs), and IWWTPs removed ARGs more efficiently than PWWTPs. The WWTP effluents greatly contributed to the ARGs pollution in the water environments of the ERAs and HZB, and the total abundance of the ARGs displayed a distance decay pattern. In coastal sediments, more ARGs were accumulated in remote sites. The correlation analysis showed that the occurrence of ARGs was more related to 16S rDNA and intI1 in the WWTPs. Three macrolides resistance genes (ermB, mphA, and vatB) had strong correlations with 16S rDNA and intI1 in all the sample groups. Our study clearly reveals the link between land WWTPs discharge and emerging pollution of ARGs in coastal environments.

    https://www.sciencedirect.com/science/article/abs/pii/S0025326X19310124