摘要

  本研究分析了重庆市两条河流中14种抗生素、4个相应的抗生素抗性基因（ARGs）和2个微生物源追踪器（MST）指标的发生情况。结果显示，12个地点共检出13种抗生素，9月份检出频率明显偏高，但浓度低于3月份。其中，红霉素（ETM）和氧氟沙星（OFL）是两个季节的主要抗生素。发现这些河流沉积物中抗生素的浓度明显高于其他河流。环境风险评估发现四种抗生素对一些敏感藻类构成高风险。对于 ARGs，它们在水域中的相对丰度高于沉积物中的丰度，3 月份高于 9 月份。相关性分析表明抗生素不是ARGs的唯一选择压力；许多环境因素，如以质量为基础的干物质含量、有机质、总有机碳、溶解有机碳、温度、氧化还原电位和亚硝酸盐，都会影响 ARGs 的发生。 MST指标分析表明，该流域主要受到人粪和猪粪污染，人粪可能是4种ARGs和5种抗生素的主要来源之一。

  In this study, the occurrence of 14 antibiotics, four corresponding antibiotic resistance genes (ARGs) and two microbial source tracker (MST) indicators were analyzed in two rivers of Chongqing city, southwest China. The results showed that 13 antibiotics were detected in all 12 sites and their detection frequencies were much higher in September, but concentrations were lower than that in March. Of them, erythromycin (ETM) and ofloxacin (OFL) were the predominant antibiotics in both seasons. The remarkably higher concentration of antibiotics in sediments of these rivers than those in other rivers were found. Environmental risk assessment found that four antibiotics posed high risk toward some sensitive algae. For ARGs, their relative abundances were higher in waters than those in sediments, higher in March than in September. Correlation analysis showed that antibiotics were not the exclusive selective pressure of ARGs; many environmental factors like dry matter contents on a mass basis, organic matter, total organic carbon, dissolved organic carbon, temperature, oxidation reduction potential and nitrite could affect the occurrence of ARGs. MST indicators analysis demonstrated that this river basin was largely polluted by human and pig feces, and human feces might be one main source of the four ARGs and five antibiotics.

  https://www.sciencedirect.com/science/article/abs/pii/S0304389420300960