摘要

       抗生素抗性基因（ARGs）作为一种威胁人类健康的新型环境污染物，已在污水处理系统的出水中被检测到。在这项研究中，使用结合纳米铁 (nFe)、超声波 (US)、活化过硫酸盐 (PS) 的工艺研究了从水中去除 ARG、16S rRNA、1 类整合子 (intI1) 和溶解有机碳 (DOC)和超滤（UF）。还研究了氧化机理。结果表明，nFe和US活化均能提高PS的氧化作用，且nFe的效果优于US。与 PS-UF 相比，nFe/PS-UF 和 US/PS-UF 显着增强了各种 ARG 和 DOC 的去除。 nFe/PS-UF 是最有效的治疗方法，将细胞相关和无细胞 ARG 分别减少 1.74-3.14-log 和 1.00-2.61-log，同时去除 30% 的 DOC。使用 PS、nFe/PS 和 US/PS 的预氧化方法显着增强了 UF 去除分子量高于 50 kDa 和低于 10 kDa 的 DOC 的功效，但去除 10 至 50 kDa 之间的 DOC 的效果降低。自由基SO4·-和·OH参与了ARGs的氧化过程。

       Antibiotic resistance genes (ARGs), as a new type of environmental pollutant that threaten human health, have been detected in the effluent of sewage treatment systems. In this study, the removal from water of ARGs, 16S rRNA, class 1 integron (intI1), and dissolved organic carbon (DOC) were investigated using processes combining nano-iron (nFe), ultrasound (US), activated persulfate (PS) and ultrafiltration (UF). The oxidation mechanism was also studied. The results showed that both nFe and US activation could improve the oxidative effect of PS, and the effect of nFe was better than that of US. Compared with PS-UF, nFe/PS-UF and US/PS-UF significantly enhanced the removal of various ARGs and DOC. nFe/PS-UF was the most effective treatment, reducing cell-associated and cell-free ARGs by 1.74–3.14-log and 1.00–2.61-log, respectively, while removing 30% of DOC. Pre-oxidation methods using PS, nFe/PS, and US/PS significantly enhanced the efficacy of UF for removing DOC with molecular weights above 50 kDa and below 10 kDa, but the removal of DOC between 10 and 50 kDa decreased. The free radicals SO4·− and ·OH were shown to participate in the process of ARGs oxidation.

https://iwaponline.com/wst/article/83/7/1578/80653/Removal-of-antibiotic-resistance-genes-from