摘要

       抗生素抗性基因（ARGs）作为新兴的环境污染物，已成为对人类健康的威胁。最近的研究表明，废水处理厂的流出物是释放到环境中的 ARG 的重要点源。在这项研究中，我们调查了混凝技术在去除处理过的废水中的 ARG 方面的有效性。具体而言，我们测量了通过应用两种凝固剂 FeCl3 和聚氯化铁（FeCl3 和聚氯化铁）去除了五个 ARG（两个磺胺类抗性基因，sulI 和 sulII，以及三个四环素抗性基因，tetO、tetW 和 tetQ）和 1 类整合子 intI1 基因（ PFC）。此外，还研究了混凝过程中溶解有机碳 (DOC)、NH3 单键 N 和总磷 (TP) 的去除。混凝过程有效地从流出物中去除了 ARG，减少了 0.5-log 到 3.1-log。在溶解的NH3单键N和DOC、intI1和sulI、sulII和tetO、sulII和tetW以及tetO和tetW之间观察到显着的去除相关性，这意味着DOC的共同去除、溶解的NH3单键N、intI1基因和不同的ARG对铁基混凝剂混凝过程中 ARG 损失的重要作用。这些结果表明混凝可能在减少废水处理厂的 ARG 中发挥有希望的作用。

       Antibiotic resistance genes (ARGs), as emerging environmental contaminants, have become a threat to human health. Recent studies have demonstrated that the effluent from wastewater treatment plants is a significant point source of ARGs released into the environment. In this study, we investigated the effectiveness of coagulation technology in the removal of ARGs from treated wastewater. Specifically, we measured the removal of five ARGs (two sulfonamide resistance genes, sulI and sulII, and three tetracycline resistance genes, tetO, tetW and tetQ) and the class 1 integron intI1 gene via the application of two coagulants: FeCl3 and polyferric chloride (PFC). Moreover, the removal of dissolved organic carbon (DOC), NH3single bondN and total phosphorus (TP) in the coagulation process was investigated. The coagulation process effectively removed ARGs from the effluent with 0.5-log to 3.1-log reductions. Significant removal correlations were observed between dissolved NH3single bondN and DOC, intI1 and sulI, sulII and tetO, sulII and tetW, and tetO and tetW, implying that the co-removal of DOC, dissolved NH3single bondN, the intI1 gene and different ARGs played an important role in ARG loss during coagulation with Fe-based coagulants. These results indicate that coagulation may play a promising role in ARG reduction in wastewater treatment plants.

https://www.sciencedirect.com/science/article/abs/pii/S0043135417300106