摘要

       本研究旨在调查处理城市、工业和混合废水的 16 个污水处理厂 (WWTP) 中的细菌群落和抗生素抗性基因 (ARG)。废水类型对细菌群落和功能有明显影响。 Nitrosomonas、Nitrospira、Hyphomicrobium和Accumulibacter是主要的功能属。分枝杆菌是主要的潜在病原体。共获得69个ARGs，不同污水处理厂的优势ARGs亚型相似。外排泵是最常见的阻力机制。铜和锌抗性基因是主要的金属抗性基因（MRGs）。废水类型影响 ARGs 和 MRGs 的分布，它们在工业废水和混合废水中更相似。 ARGs 的共存存在于 ARG 类型内部或之间，并且它们也与 MRGs、一些功能和致病属或环境因素呈正相关。本研究进一步了解不同污水处理厂中细菌群落、ARGs 和 MRGs 之间的相互作用。

       This study aimed to investigate the bacterial communities and antibiotic resistance genes (ARGs) in 16 wastewater treatment plants (WWTPs) treating municipal, industrial and mixed wastewater. Wastewater types showed obvious effects on bacterial communities and functions. Nitrosomonas, Nitrospira, Hyphomicrobium and Accumulibacter were the main functional genera. Mycobacterium was the dominant potential pathogens. A total of 69 ARGs were obtained, and the dominant ARGs subtypes were similar in different WWTPs. Efflux pumps were the most common resistance mechanisms. Copper and zinc resistance genes were the main metal resistance genes (MRGs). Wastewater types affected the distributions of ARGs and MRGs, and they were more similar in industrial and mixed wastewater. The co-occurrence of ARGs existed within or across ARG types, and they were also positively linked to MRGs, some functional and pathogenic genera or environmental factors. This study furthers the understanding of interactions between bacterial communities, ARGs and MRGs in different WWTPs.

https://www.sciencedirect.com/science/article/abs/pii/S0960852418310496