摘要

       在这项研究中，研究了单 SS、MW-SS:FW 和 SS:MW-FW 的厌氧消化，以了解 ARG 的命运及其驱动因素。 厌氧消化可有效减少金属抗性基因 (MRG)，并可降低 blaOXA-1、sulI 和 tetG 的丰度，而 sulII 在共消化中和 blaTEM 和 ereA 仅在 MW-SS 中。 ARGs 的减少可能部分归因于 MRGs 反映的重金属共选择压力的减少。 然而，mefA/E、ermB、ermF、tetM 和 tetX 的丰度显着增加。 与单 SS 相比，厌氧共消化，尤其是 MW-SS，可以降低总 ARGs 丰度，细菌群落的进化是 ARGs 命运的主要驱动因素。 

       In this study, anaerobic digestion of mono-SS, MW-SS:FW and SS:MW-FW was investigated to understand the fate of ARGs and its drivers. Anaerobic digestion was effective for the reduction of metal resistance genes (MRGs), and could reduce the abundance of blaOXA-1, sulI and tetG, while sulII in co-digestion and blaTEM and ereA only in MW-SS. ARGs reduction could be partly attributed to the reduction of co-selective pressure from heavy metals reflected by MRGs. However, the abundance of mefA/E, ermB, ermF, tetM and tetX increased significantly. Anaerobic co-digestion, especially for MW-SS, could reduce total ARGs abundance compared with mono-SS, and evolution of bacterial community was the main driver for the fate of ARGs.

https://www.sciencedirect.com/science/article/abs/pii/S0960852416303078