摘要

       抗生素抗性基因 (ARG) 很普遍，但只有在病原体中存在时才会引起问题。 经常发生抗生素抗性选择和传播的环境可能以水平可转移 ARG 的高丰度和多样性为特征。 然而，对于大多数类型的环境，包括人类和动物，缺乏 ARG 的大规模定量数据，以及对潜在共选择剂（如杀生物剂和金属）的抗性基因的数据。 这种缺乏阻碍了对风险环境的有效识别。 

       Antibiotic resistance genes (ARGs) are widespread but cause problems only when present in pathogens. Environments where selection and transmission of antibiotic resistance frequently take place are likely to be characterized by high abundance and diversity of horizontally transferable ARGs. Large-scale quantitative data on ARGs is, however, lacking for most types of environments, including humans and animals, as is data on resistance genes to potential co-selective agents, such as biocides and metals. This paucity prevents efficient identification of risk environments.

https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-016-0199-5?luicode=10000011&lfid=231522type%3D1%26t%3D10%26q%3D%23%E7%A9%BA%E6%B0%94%E4%BC%A0%E6%92%AD%23&featurecode=1&u=https%3A%2F%2Fmicrobiomejournal.biomedcentral.com%2Farticles%2F10.1186%2Fs40168-016-0199-5