摘要

       传统的城市污水处理厂 (UWTP) 在消除大多数新出现的污染物 (CEC) 方面效率不足，包括抗生素、抗生素抗性细菌和抗生素抗性基因 (ARB 和 ARG)。这些污染物导致一些对自然和人类健康的担忧。这项工作讨论了处理城市污水 (UWW) 以消除 CEC 和 ARB 和 ARG 的最佳可用技术 (BAT) 的性能。臭氧化、活性炭吸附、化学消毒剂、紫外线辐射、高级氧化工艺 (AOP) 和膜过滤都在争论，以期有效减少 CEC 和 ARB 和 ARG 的潜力。比较可能涉及 BAT 的治疗序列。尽管在应用 AOP 和了解其去除 ARB 和 ARG 的机制方面取得了巨大的进步，但可能会产生现有抗生素的转化产物 (TP)，这些产物的生物可分解性较差、毒性更大、生物强度更大、并列到母体化合物。因此，必须集中精力定义此类 TP 的结构，并证明这些 TP 是否保留其核心部分，负责抗生素的抗微生物活性，可能包括对周围微生物的抗微生物性。

       Traditional urban wastewater treatment plants (UWTPs) are deficiently efficient in eliminating most contaminants of emerging concern (CECs), comprising antibiotics, antibiotic resistant bacteria and antibiotic resistance genes (ARB & ARGs). Such pollutants lead to some worry for nature and human health. This work discusses the performance of the best available technologies (BATs) for dealing with urban wastewater (UWW) to eliminate CECs and ARB & ARGs. Ozonation, activated carbon adsorption, chemical disinfectants, UV radiation, advanced oxidation processes (AOPs) and membrane filtration are debated with a view to their potential to efficaciously reduce CECs and ARB & ARGs. Probable treatment trains involving the BATs are compared. In spite of the huge improvements acquired in terms of applying AOPs and understanding their mechanisms in removing ARB & ARGs, transformation products (TPs) of the antibiotics existing may be generated, which may be less bio-decomposable, more poisonous and biologically strong, juxtaposed to the parent compounds. Therefore, attempts have to be concentrated on defining the structure of such TPs and proving if these retain their core moieties, responsible for the antimicrobial activity of the antibiotic, probably comprising antimicrobial resistance to the surrounding microbes.

https://www.scirp.org/journal/paperinformation.aspx?paperid=98871