摘要

       该研究首次报告了不同均相高级氧化工艺 (AOP)（H2O2/UV-C、PMS/UV-C 和 PMS/Fe(II)/UV-C）在去除抗生素方面的全面应用(ABs) 和来自 Estiviel 废水处理厂 (WWTP)（西班牙托莱多）的废水中的抗生素抗性基因 (ARG)。
在低剂量（0.05-0.5mM）和极短的 UV-C 接触时间（4-18 秒）下测试基于 H2O2 和过氧单硫酸盐的光解分解的 AOP 被证明比单独的 UV-C 辐射更有效地去除分析的 AB。 PMS (0.5mM) 结合 UV-C（7 秒接触时间）是去除 AB 方面最有效的处理方法：在废水中检测到的 10 种 AB 中有 7 种比使用其他氧化剂更有效地去除。就 ARGs 去除效率而言，UV-C 似乎是最有效的处理方法，尽管 H2O2/UV-C、PMS/UV-C 和 PMS/Fe(II)/UV-C 被认为会产生更高浓度的自由基。结果表明，ABs 和 ARGs 去除率最高的处理并不重合，这可能是由于 DNA 和氧化剂在吸收紫外线光子方面的竞争，减少了 DNA 的直接光解作用。虽然通过羟基和硫酸根自由基的产生改善了光解 ABs 的去除，但在 ARGs 的情况下会发生相反的行为。这些结果表明，为了优化废水处理过程，必须在 AB 和 ARG 去除之间实现折衷。

       This research reports for the first time the full-scale application of different homogeneous Advanced Oxidation Processes (AOPs) (H2O2/UV-C, PMS/UV-C and PMS/Fe(II)/UV-C) for the removal of antibiotics (ABs) and antibiotic resistance genes (ARGs) from wastewater effluent at Estiviel wastewater treatment plant (WWTP) (Toledo, Spain).
AOPs based on the photolytic decomposition of H2O2 and peroxymonosulfate tested at low dosages (0.05–0.5 mM) and with very low UV-C contact time (4–18 s) demonstrated to be more efficient than UV-C radiation alone on the removal of the analyzed ABs. PMS (0.5 mM) combined with UV-C (7 s contact time) was the most efficient treatment in terms of AB removal: 7 out of 10 ABs detected in the wastewater were removed more efficiently than using the other oxidants. In terms of ARGs removal efficiency, UV-C alone seemed the most efficient treatment, although H2O2/UV-C, PMS/UV-C and PMS/Fe(II)/UV-C were supposed to generate higher concentrations of free radicals. The results show that treatments with the highest removal of ABs and ARGs did not coincide, which could be attributed to the competition between DNA and oxidants in the absorption of UV photons, reducing the direct photolysis of the DNA. Whereas the photolytic ABs removal is improved by the generation of hydroxyl and sulfate radicals, the opposite behavior occurs in the case of ARGs. These results suggest that a compromise between ABs and ARGs removal must be achieved in order to optimize wastewater treatment processes.

https://www.sciencedirect.com/science/article/abs/pii/S0048969718341160