摘要

       尽管抗生素耐药性是一个重要且日益严重的公共卫生问题，但噬菌体（噬菌体）对环境中抗生素耐药基因 (ARG) 的动员的贡献尚未得到广泛研究。 然而，最近的研究表明，噬菌体在 ARG 的获取、维持和传播中发挥了比以前预期的重要作用。 这篇意见文章提供了有关噬菌体对环境抗生素耐药性的贡献的最新信息。 更好地了解促进抗生素耐药性的机制和因素可能会大大有助于控制策略的实施。

       Although antibiotic resistance represents a significant and growing public health concern, the contribution of bacteriophages (phages) to the mobilization of antibiotic resistance genes (ARGs) in the environment has not been extensively studied. Recent studies, however, suggest that phages play an important role in the acquisition, maintenance, and spread of ARGs than previously expected. This Opinion article offers an update on the contribution of phages to environmental antibiotic resistance. A better understanding of the mechanisms and factors that promote antibiotic resistance may significantly contribute to the implementation of control strategies.

https://www.sciencedirect.com/science/article/abs/pii/S0966842X19300599