摘要
      近年来，土壤污染已成为全球关注的问题。蚯蚓能够承受高浓度的土壤污染物，并在有效清除这些污染物方面发挥着重要作用。使用蚯蚓的蚯蚓堆肥过程越来越多地用于将各种有机废物转化为具有减少的生物污染物的蚯蚓粪。
动物粪便中的抗生素抗性基因（ARGs）使废物来源的再利用变得困难。Vermicompositing是一种潜在的成功废物资源管理方法，但ARG在这一过程中的命运因各种原料和操作条件而变得复杂。本文的目的是研究影响蚯蚓堆肥中ARG多样性的生物和非生物元素及其可能的过程。堆肥过程中影响ARG命运的直接因素包括生物成分的动态变化，如细菌群落和可移动遗传元素（MGE）。然而，大多数主要的非生物因素，如温度、pH、营养平衡、水分含量和重金属，通过改变微生物种群周期和MGE的丰富度，间接影响ARG的丰度。降低ARGs的选择性或共选择性压力，杀死ARGs潜在的宿主细菌，改变细菌种群组织，减少细菌的细胞-细胞相互作用，这些都是通过各种调节方法消除ARGs可能的技术。最后，对生物污染土壤蚯蚓修复的未来前景进行了展望，以鼓励蚯蚓修复在生物污染土壤中的进一步研究和应用。
Abstract
Soil pollution has become a global problem that has attracted worldwide attention in recent years. Earthworms can withstand high concentrations of soil pollutants and play an important role in their effective removal. The vermicomposting process using earthworms is increasingly used for the conversion of various organic wastes into vermicast with reduced bio-contaminant.

Antibiotic resistance genes (ARGs) in animal feces make it difficult to reuse waste sources. Vermicomposting is a potentially successful approach to waste resource management, but the fate of ARGs in this process is complicated by various feedstocks and operating conditions. The objective of this article is to examine the biotic and abiotic elements that influence ARG diversity in vermicomposting and their likely processes. Direct factors affecting the fate of ARG during composting include dynamic changes in biotic components such as the bacterial community and mobile genetic elements (MGEs). However, most major abiotic factors such as temperature, pH, nutrient balance, moisture content, and heavy metals indirectly affect the abundance of ARG, by altering the microbial population cycle and the richness of MGEs. Reducing selective or coselective pressure on ARGs, killing the potential host bacteria of ARGs, altering bacterial population organization, and decreasing cell–cell interaction of bacteria are all possible techniques for eliminating ARGs in various regulatory approaches. Finally, future prospects for vermiremediation of bio-contaminated soils are presented to encourage further studies and applications of vermiremediation in biologically contaminated soils.

https://www.sciencedirect.com/science/article/abs/pii/B9780323959988000054