摘要
      抗生素、抗生素抗性细菌（ARB）和抗生素抗性基因（ARGs）在再生水中无处不在，对人类和生态健康构成潜在威胁。目前，再生水的回用技术受到了广泛关注，但对再生水中抗生素、ARB和ARGs的去除研究还不够充分。本研究使用Ag/SnO2-Sb纳米颗粒（TNTs-Ag/SnO2-Sb）修饰的TiO2纳米管阵列（TNTs）作为阳极，Ti Pd/SnO2-Sb作为阴极，构建了一个高效的光电催化（PEC）系统。在该系统中，99.9%的ARB在20min内失活，同时ARGs在30min内被去除，抗生素在1h内几乎完全降解。此外，还研究了系统参数对抗生素、ARB和ARGs去除的影响。通过添加过硫酸盐验证了该体系的氧化还原性能。大肠杆菌作为水生环境中的代表性微生物，用于评价PEC处理的氯霉素（CAP）溶液的生态毒性。经PEC处理后，CAP溶液的生态毒性显著降低。此外，使用液相色谱-串联质谱法（LC-MS/MS）鉴定了CAP的转化中间体，并提出了可能的降解途径。这项研究可以为控制抗生素耐药性和保护再生水质量提供一种潜在的替代方法。
Abstract
Antibiotics, antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) are ubiquitous in the reclaimed water, posing a potential threat to human and ecological health. Nowadays, the reuse technology of reclaimed water has been widely concerned, but the removal of antibiotics, ARB and ARGs in reclaimed water has not been sufficiently studied. This study used TiO2 nanotube arrays (TNTs) decorated with Ag/SnO2-Sb nanoparticles (TNTs-Ag/SnO2-Sb) as the anode and Ti-Pd/SnO2-Sb as the cathode to construct an efficient photoelectrocatalytic (PEC) system. In this system, 99.9% of ARB was inactivated in 20 min, meanwhile, ARGs was removed within 30 min, and antibiotics were almost completely degraded within 1 h. Furthermore, the effects of system parameters on the removals of antibiotics, ARB and ARGs were also studied. The redox performance of the system was verified by adding persulfate. Escherichia coli, as a representative microorganism in aquatic environments, was used to evaluate the ecotoxicity of PEC treated chloramphenicol (CAP) solution. The ecotoxicity of CAP solution was significantly reduced after being treated by PEC. In addition, transformation intermediates of CAP were identified using liquid chromatography-tandems mass spectrometry (LC-MS/MS) and the possible degradation pathways were proposed. This study could provide a potential alternative method for controlling antibiotic resistance and protecting the quality of reclaimed water.

https://www.sciencedirect.com/science/article/abs/pii/S0304389421025218