摘要
抽象图像
为了防止抗生素耐药性扩散到环境中，我们应该充分管理废水处理，以同时去除抗生素、抗生素耐药性细菌（ARB）和抗生素耐药性基因（ARGs）。在此，我们在导电碳布上通过相反转制备了多功能电活性聚偏氟乙烯超滤膜（C/PVDF）。该膜不仅对ARB和ARGs具有优异的保留能力，而且作为电极表现出高的氧化能力。值得注意的是，磺胺甲恶唑的降解主要涉及阳极膜的羟基化和水解，在+4V时降解效率高达81.5%。两种电过滤过程都表现出显著的ARB失活，阳极过滤优于阴极过滤。此外，位于基因组中的细胞内ARGs（iARGs）的降解比位于质粒中的更有效，并且这些降解效率在−2V时高于+2V。细胞外ARGs的降解效率相反，低于iARGs。与常规过滤相比，电活性超滤膜在处理废水过程中，在−2V时的归一化通量提高了18.0%，在+2V时提高了15.9%，在+4V时提高30.4%，证实了其防污性能和实际应用的可行性。
Abstract
Abstract Image
To combat the spread of antibiotic resistance into the environment, we should adequately manage wastewater effluent treatment to achieve simultaneous removal of antibiotics, antibiotic resistant bacteria (ARB), and antibiotic resistance genes (ARGs). Herein, we fabricate a multifunctional electroactive poly(vinylidene fluoride) ultrafiltration membrane (C/PVDF) by phase inversion on conductive carbon cloth. The membrane possesses not only excellent retention toward ARB and ARGs but also exhibits high oxidation capacity as an electrode. Notably, sulfamethoxazole degradation involving hydroxylation and hydrolysis by the anode membrane is predominant, and the degradation efficiency is up to 81.5% at +4 V. Both electro-filtration processes exhibit significant ARB inactivation, anode filtration is superior to cathode filtration. Moreover, the degradation of intracellular ARGs (iARGs) located in the genome is more efficient than those located in the plasmid, and these degradation efficiencies at −2 V are higher than +2 V. The degradation efficiencies of extracellular ARGs (eARGs) are opposite and are lower than iARGs. Compared with regular filtration, the normalized flux of electroactive ultrafiltration membrane is improved by 18.0% at −2 V, 15.9% at +2 V, and 30.4% at +4 V during treating wastewater effluent, confirming its antifouling properties and feasibility for practical application.

https://pubs.acs.org/doi/abs/10.1021/acs.est.2c00268