摘要
出身背景
肠道微生物组为抗生素耐药性基因（ARGs）提供了一个库。在以后的生活中，新生儿微生物组比已建立的微生物组更容易受到外部因素的干扰。
目标
在这篇综述中，我们系统地总结了研究新生儿肠道耐药性的研究。
数据来源
检索MEDLINE和Embase数据库。
研究合格标准
我们纳入了使用分子诊断法调查新生儿粪便或直肠拭子中ARGs的原始研究。
数据合成方法
两位作者独立提取了数据，这些数据汇总在表格中。
Abstract
Background
The intestinal microbiome provides a reservoir for antibiotic resistance genes (ARGs). The neonatal microbiome is more susceptible to disturbance from external factors than the established microbiome in later life.

Objectives
In this review, we systematically summarize studies which investigated the intestinal resistome in neonates.

Data sources
MEDLINE and Embase databases were searched.

Study eligibility criteria
We included original studies which investigated ARGs in stool or rectal swabs in neonates using molecular diagnostics.

Methods of data synthesis
Two authors independently extracted data, which were summarized in tables.

https://www.sciencedirect.com/science/article/abs/pii/S1198743X22003780