摘要
      磺胺甲基恶唑（SMX）的有效降解对缓解环境污染具有重要意义。在本研究中，比较了普通序批式活性污泥系统（SBR）和蒙脱石（MMT）系统对不同浓度SMX的降解能力。与SBR体系相比，MMT体系表现出更高的稳定性和降解能力。紧密结合的胞外聚合物（TB-EPS）组成的变化可能是观察到的系统稳定性的关键。高浓度的SMX抑制了SBR的降解性能。MMT的补充减少了抗生素抗性基因（ARGs）的产生。Thauera是一种能够降解SMX的基因，其在MMT系统中的丰度达到7.84%。作为ARGs的潜在宿主，白头翁和Caldilineacea的比例与磺酰胺抗性基因（sul1和sul2）显著相关。总的来说，MMT补充系统被发现是治疗抗生素的一种有利方法。
Abstract
The effective degradation of Sulfamethoxazole (SMX) is of great importance to alleviate environmental pollution. In this study, the degradation capacity of an ordinary sequencing batch activated sludge system (SBR) and montmorillonite (MMT) system was compared for their ability to degrade different concentrations of SMX. Compared with SBR system, the MMT system exhibited higher stability and degradation capacity. The changes in the composition of tightly bound extracellular polymeric substances (TB-EPS) were likely key to the observed stability of the system. High concentrations of SMX inhibited the degradation performance of SBR. MMT-supplemented reduced the generation of antibiotic resistance genes (ARGs). Thauera is a gene that is able to degrade SMX, and its abundance in MMT system reached 7.84%. As potential hosts of ARGs, the proportions of Paenarthrobacter and Caldilineacea were significantly correlated with sulfonamide resistance genes (sul1 and sul2). Overall, MMT-supplemented system was found to be a favorable method of treating antibiotic.

https://www.sciencedirect.com/science/article/abs/pii/S0960852422004278