摘要

抗生素耐药性是对人类健康的一个快速增长的威胁。 环境 - 包括动物和植物 - 既是抗生素抗性病原体的传播途径，又是抗性基因的来源。 食品供应链通过有时（由于在农业和水产养殖业中使用抗生素）的途径将细菌的环境栖息地与人类连接起来，其中包括对抗性的大量选择。 根据国际食品标准，在食品生产风险分析中应考虑食源性抗性的选择和传播。 高通量测序和宏基因组学可以有助于理解食品供应链中的这些传输和选择过程。

Antibiotic resistance is a rapidly growing threat to human health. The environment – including animals and plants – functions both as a transmission route for antibiotic resistant pathogens and a source of resistance genes. The food supply chain connects environmental habitats for bacteria with humans through a route that sometimes – due to use of antibiotics in both agriculture and aquaculture – includes substantial selection for resistance. According to international food standards, selection and dissemination of foodborne resistance should be considered in the risk analysis of food production. High-throughput sequencing and metagenomics could contribute to understanding these transmission and selection processes in the food supply chain.

https://www.sciencedirect.com/science/article/pii/S2214799317300140