摘要

这项工作的目的是研究在微生物燃料电池（MFCs）中产甲烷菌活动受限的条件下磺胺嘧啶（SDZ）的生物降解效率，抗生素抗性基因（ARGs）的发展以及微生物群落的迁移。 结果表明，在MFC和开路控制中，SDZ的去除性能均随着甲烷源的抑制而降低。 抑制产甲烷菌甚至增强了ARGs的相对丰度。 获得了SDZ的生物降解机理，其中SDZ最初分为苯胺和嘧啶-2-基氨基磺酸，然后转化为小分子。 发现土杆菌是优势微生物，表明它具有降解MFC中SDZ的潜力。 这些发现表明，通过MFC中产甲烷菌的抑制作用，在电力生产与SDZ去除和ARG的发展之间需要进行权衡。

The aim of this work was to study sulfadiazine (SDZ) biodegradation efficiency, antibiotic resistance genes (ARGs) development and shift of microbial communities under conditions of limited methanogens activity in Microbial fuel cells (MFCs). The results indicated that the removal performance of SDZ was decreased with the suppression of methanogens in both MFCs and open-circuit controls. The relative abundances of ARGs were even enhanced by the inhibition of methanogens. The biodegradation mechanism of SDZ was obtained, in which SDZ was initially divided into aniline and pyrimidin-2ylsulfamic acid, then converted into small molecules. Geobacter was found as the dominant microorganism, indicating its potential to degrade SDZ in the MFCs. These findings suggest there is a trade-off between electricity production and SDZ removal and ARG development by the mean of methanogen inhibition in MFCs.

https://www.sciencedirect.com/science/article/pii/S0960852419302974