摘要

       作为新兴的微生物污染物，抗生素抗性基因 (ARG) 在水环境中广泛存在，包括源水，它们可能通过增强机会性病原体对某些抗生素的抗性而进入供水系统并危害公共健康。在本研究中，我们使用实时 PCR 研究了水处理如何影响大型饮用水处理厂一年内的 ARGs 水平。监测源水和各处理出水口和自来水中的16s rRNA基因和11个ARG家族，包括tetA、tetG、aacC1、strA、ermB、cmlA5、vanA、dfrA1、sulII、blaTEM-1和blaoxa-1 .结果表明，检测到 9 个 ARG 家族的水平相对较高，例如，7 月份在成品水和自来水中检测到 sulII 基因约为 104 个拷贝 mL-1，而在成品水和自来水中检测到 105 个拷贝 mL-1，其相对浓度始终保持一致。高的。降低 ARGs 绝对浓度的处理方法包括砂滤、混凝/沉淀和两级 O3-BAC 过滤，而分布可将 ARGs 平均增加 0.50 log。

       As an emerging microbial pollutant, antibiotic resistance genes (ARG) are widely present in the water environment, including source water. They may enter the water supply system and endanger public health by enhancing the resistance of opportunistic pathogens to certain antibiotics. In this study, we used real-time PCR to study how water treatment affects the level of ARGs in a large drinking water treatment plant within one year. Monitor the 16s rRNA genes and 11 ARG families in the source water and the treated water outlets and tap water, including tetA, tetG, aacC1, strA, ermB, cmlA5, vanA, dfrA1, sulII, blaTEM-1 and blaoxa-1. The results show that , The levels of 9 ARG families were relatively high. For example, in July, about 104 copies of sulII gene were detected in product water and tap water, while 105 copies of mL-1 were detected in product water and tap water. 1. The relative concentration is always the same. High. Treatment methods to reduce the absolute concentration of ARGs include sand filtration, coagulation/sedimentation and two-stage O3-BAC filtration, and the distribution can increase ARGs by an average of 0.50 log.

https://academic.oup.com/femsec/article/92/5/fiw065/2470079?login=true