摘要

       目前动物粪便处理的工作不符合要求的标准，因此不应该反映抗生素耐药性控制的实际表现。 因此，本研究以磺胺甲恶唑（SMX）为典型抗生素进行了温控好氧堆肥。 四种不同处理的结果表明，温度、含水量、C/N 比、EC 和 pH 值均无显着差异（p > 0.05）。 抗生素抗性基因 (ARGs) 在嗜热期的前 10 天显着减少，但 sul1 和 sul2 的丰度在 30 天后大幅增加。 此外，在堆肥后期，ARGs 之间密切相关。 堆肥特性的显着影响，尤其是温度对细菌群落的影响，然后对 ARGs 丰度产生积极影响。 这些发现证明标准堆肥仍然不足以控制抗生素耐药性。 
       The current work of animal manure treatment does not meet the required standards, so it should not reflect the actual performance of antibiotic resistance control. Therefore, this study used sulfamethoxazole (SMX) as a typical antibiotic for temperature-controlled aerobic composting. The results of the four different treatments showed that there were no significant differences in temperature, water content, C/N ratio, EC, and pH (p> 0.05). Antibiotic resistance genes (ARGs) decreased significantly during the first 10 days of the thermophilic period, but the abundance of sul1 and sul2 increased significantly after 30 days. In addition, in the later stage of composting, ARGs are closely related. The significant influence of composting characteristics, especially the influence of temperature on the bacterial community, then has a positive effect on the abundance of ARGs. These findings prove that standard compost is still insufficient to control antibiotic resistance. 

https://www.sciencedirect.com/science/article/abs/pii/S0960852420316771