摘要

       本研究中出现了8种抗生素[3种四环素（TCs）、4种磺胺类和1种甲氧苄氨嘧啶（TMP）]、12种抗生素抗性基因（ARGs）（10个tet、2个sul）、4种细菌[无抗生素、评估了两个污水处理厂 (WWTP) 中的抗 TC、抗磺胺甲恶唑 (SMX) 和抗双] 和 intI1，并研究了它们对下游湖泊的影响。两个污水处理厂的出水表现出一些相似之处，但丰度和去除率差异很大。结果显示，生物处理主要去除抗生素和 ARG，而发现物理技术可以消除抗生素抗性细菌 (ARB) 的丰度（每个约 1 log）。紫外线消毒并没有显着提高去除效率，并且从剩余污泥中释放出大量可用的目标污染物可能对人类和环境构成威胁。不同的抗生素对下游湖泊表现出不同的影响，观察到磺胺二甲嘧啶（SM2）和SMX的浓度大幅增加。由于流出物的高输入，总 ARG 丰度上升了约 0.1 log，并且一些 ARG（例如，tetC、intI1、tetA）增加。此外，湖泊中ARB变异的丰度也发生了变化，但下游采样点4种细菌的丰度保持稳定。

       In this study, 8 antibiotics [3 tetracyclines (TCs), 4 sulfonamides and 1 trimethoprim (TMP)], 12 antibiotic resistance genes (ARGs) (10 tet, 2 sul) appeared in this study ), 4 kinds of bacteria [no antibiotics, evaluated anti-TC, anti-sulfamethoxazole (SMX) and anti-double] and intI1 in two sewage treatment plants (WWTP), and studied their effects on downstream lakes. The effluents of the two sewage treatment plants show some similarities, but the abundance and removal rate are quite different. The results showed that biological treatment mainly removes antibiotics and ARG, while physical techniques have been found to eliminate the abundance of antibiotic-resistant bacteria (ARB) (about 1 log each). Ultraviolet disinfection does not significantly improve the removal efficiency, and the release of a large amount of available target pollutants from the remaining sludge may pose a threat to humans and the environment. Different antibiotics showed different effects on the downstream lakes, and a large increase in the concentration of sulfamethazine (SM2) and SMX was observed. Due to the high input of the effluent, the total ARG abundance increased by about 0.1 log, and some ARGs (for example, tetC, intI1, tetA) increased. In addition, the abundance of ARB variation in the lake has also changed, but the abundance of the four bacteria in the downstream sampling points remained stable.

https://link.springer.com/article/10.1007%2Fs11356-015-5916-2