摘要
      抗生素的滥用增加了抗生素耐药性基因（ARGs）的流行率，由于其普遍存在和持久的性质，ARGs被认为是一类关键的环境污染物。先前的研究报道了生物电芬顿工艺在抗生素去除和ARGs控制方面的潜力。然而，由微生物燃料电池触发的生物电芬顿过程中ARGs的产生和命运是罕见的。在本研究中，诺氟沙星（NFLX）在两天内的平均残留浓度分别为2.02、6.07和14.84 mg/L，在初始抗生素浓度为10、20和40 mg/L时，NFLX的平均去除率分别为79.8%、69.6%和62.9%。在所有过程中最普遍的耐药基因类型是氟喹诺酮类抗生素基因。此外，变形杆菌是携带ARG的主要细菌。总体而言，本研究可以从生态安全的角度为生物-电-芬顿系统有效处理高抗生素废水以更好地控制ARGs提供理论支持。
Abstract
The misuse of antibiotics has increased the prevalence of antibiotic resistance genes (ARGs), considered a class of critical environmental contaminants due to their ubiquitous and persistent nature. Previous studies reported the potentiality of bio-electro-Fenton processes for antibiotic removal and ARGs control. However, the production and fate of ARGs in bio-electro-Fenton processes triggered by microbial fuel cells are rare. In this study, the norfloxacin (NFLX) average residual concentrations within two days were 2.02, 6.07 and 14.84 mg/L, and the average removal efficiency of NFLX was 79.8 %, 69.6 % and 62.9 % at the initial antibiotic concentrations of 10, 20 and 40 mg/L, respectively. The most prevalent resistance gene type in all processes was the fluoroquinolone antibiotic gene. Furthermore, Proteobacteria was the dominant ARG-carrying bacteria. Overall, this study can provide theoretical support for the efficient treatment of high antibiotics-contained wastewater by bio-electro-Fenton systems to better control ARGs from the perspective of ecological security.

https://www.sciencedirect.com/science/article/abs/pii/S0960852422014432