摘要

作为新兴的环境污染物，抗生素抗性基因（ARG）已成为对人类健康的威胁。最近的研究表明，污水处理厂的废水是释放到环境中的ARG的重要来源。在这项研究中，我们调查了凝结技术在处理废水中除去ARGs的有效性。具体而言，我们通过应用两种促凝剂：FeCl3和聚氯化铁（三氯乙烯）来测量五种ARG（两种磺胺抗性基因，sulI和sulII以及三种四环素抗性基因，tetO，tetW和tetQ）和1类整合子intI1基因的去除PFC）。此外，研究了混凝过程中溶解有机碳（DOC），NH3N和总磷（TP）的去除。凝结过程有效地从废水中去除了ARGs，其中0.5-log减少到3.1-log。在溶解的NH3N和DOC，intI1和sulI，sulII和tetO，sulII和tetW以及tetO和tetW之间观察到显着的去除相关性，这意味着DOC的共同去除，溶解的NH3N，intI1基因和不同的ARG起到了重要作用在用铁基凝结剂凝固过程中ARG损失。这些结果表明，凝结可能在污水处理厂的ARG减少方面起到很大的作用。

Antibiotic resistance genes (ARGs), as emerging environmental contaminants, have become a threat to human health. Recent studies have demonstrated that the effluent from wastewater treatment plants is a significant point source of ARGs released into the environment. In this study, we investigated the effectiveness of coagulation technology in the removal of ARGs from treated wastewater. Specifically, we measured the removal of five ARGs (two sulfonamide resistance genes, sulI and sulII, and three tetracycline resistance genes, tetO, tetW and tetQ) and the class 1 integron intI1 gene via the application of two coagulants: FeCl3 and polyferric chloride (PFC). Moreover, the removal of dissolved organic carbon (DOC), NH3N and total phosphorus (TP) in the coagulation process was investigated. The coagulation process effectively removed ARGs from the effluent with 0.5-log to 3.1-log reductions. Significant removal correlations were observed between dissolved NH3N and DOC, intI1 and sulI, sulII and tetO, sulII and tetW, andtetO and tetW, implying that the co-removal of DOC, dissolved NH3N, the intI1 gene and different ARGs played an important role in ARG loss during coagulation with Fe-based coagulants. These results indicate that coagulation may play a promising role in ARG reduction in wastewater treatment plants.

https://www.sciencedirect.com/science/article/pii/S0043135417300106